Interações medicamentosas
Dronedarone + Hydroxychloroquine
Gravidade: Contraindicada
Dronedarone and Hydroxychloroquine: contraindicated interaction.
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Resumo
Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
O que esta interação significa em palavras simples
Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dronedarone belongs to Cardiovascular; Hydroxychloroquine belongs to Musculoskeletal.
Por que acontece
Additive delayed ventricular repolarization through potassium channel blockade.
O que fazer
Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicada
- Cisapride + Hydroxychloroquine Contraindicada
- Hydroxychloroquine + Pimozide Contraindicada
- Hydroxychloroquine + Thioridazine Contraindicada
- Hydroxychloroquine + Vandetanib Contraindicada
- Adagrasib + Hydroxychloroquine Grave
Outras interações de Dronedarone
- Adagrasib + Dronedarone Contraindicada
- Amiodarone + Dronedarone Contraindicada
- Arsenic trioxide + Dronedarone Contraindicada
- Artemether / lumefantrine + Dronedarone Contraindicada
- Atazanavir + Dronedarone Contraindicada
- Azithromycin + Dronedarone Contraindicada
Perguntas frequentes
Can I take Dronedarone with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
How serious is the interaction between Dronedarone and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Pimozide. The full list is on the Hydroxychloroquine page.
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