Interações medicamentosas
Hydroxychloroquine + Thioridazine
Gravidade: Contraindicada
Hydroxychloroquine and Thioridazine: contraindicated interaction.
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Resumo
Thioridazine is strongly associated with QT prolongation and torsades de pointes, and hydroxychloroquine adds to the risk. Thioridazine labeling contraindicates use with other drugs that prolong the QT interval.
O que esta interação significa em palavras simples
Hydroxychloroquine and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Hydroxychloroquine belongs to Musculoskeletal; Thioridazine belongs to Central Nervous System.
Por que acontece
Additive QT prolongation via potassium channel blockade.
O que fazer
Do not combine; use an alternative antipsychotic or a different antimalarial or antirheumatic agent.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicada
- Cisapride + Hydroxychloroquine Contraindicada
- Dronedarone + Hydroxychloroquine Contraindicada
- Hydroxychloroquine + Pimozide Contraindicada
- Hydroxychloroquine + Vandetanib Contraindicada
- Adagrasib + Hydroxychloroquine Grave
Outras interações de Thioridazine
- Abiraterone + Thioridazine Contraindicada
- Adagrasib + Thioridazine Contraindicada
- Amiodarone + Thioridazine Contraindicada
- Amisulpride + Thioridazine Contraindicada
- Amitriptyline + Thioridazine Contraindicada
- Amoxapine + Thioridazine Contraindicada
Perguntas frequentes
Can I take Hydroxychloroquine with Thioridazine?
MediHelp rates the interaction as contraindicated. Hydroxychloroquine and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine is strongly associated with QT prolongation and torsades de pointes, and hydroxychloroquine adds to the risk. Thioridazine labeling contraindicates use with other drugs that prolong the QT interval.
How serious is the interaction between Hydroxychloroquine and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use an alternative antipsychotic or a different antimalarial or antirheumatic agent.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
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