Interações medicamentosas
Colchicine + Fluvastatin
Gravidade: Moderada
Colchicine and Fluvastatin: moderate interaction.
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Resumo
Both drugs can cause myopathy, and the combination has been linked to rhabdomyolysis. Risk is greater in older patients and those with renal impairment.
O que esta interação significa em palavras simples
Colchicine and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colchicine belongs to Genitourinary; Fluvastatin belongs to Cardiovascular.
Por que acontece
Additive myotoxicity.
O que fazer
Monitor for muscle pain, weakness and dark urine, and check creatine kinase if symptoms occur. Consider temporary statin interruption during colchicine courses in high-risk patients.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Colchicine
- Clarithromycin + Colchicine Contraindicada
- Cobicistat + Colchicine Contraindicada
- Colchicine + Cyclosporine Contraindicada
- Colchicine + Ensitrelvir Contraindicada
- Colchicine + Levoketoconazole Contraindicada
- Colchicine + Nirmatrelvir Contraindicada
Outras interações de Fluvastatin
- Cyclosporine + Fluvastatin Grave
- Cyclosporin + Fluvastatin Grave
- Fluvastatin + Gemfibrozil Grave
- Fluvastatin + Letermovir Grave
- Fluvastatin + Red yeast rice Grave
- Apalutamide + Fluvastatin Moderada
Perguntas frequentes
Can I take Colchicine with Fluvastatin?
MediHelp rates the interaction as moderate. Colchicine and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause myopathy, and the combination has been linked to rhabdomyolysis. Risk is greater in older patients and those with renal impairment.
How serious is the interaction between Colchicine and Fluvastatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for muscle pain, weakness and dark urine, and check creatine kinase if symptoms occur. Consider temporary statin interruption during colchicine courses in high-risk patients.
What other medicines interact with Colchicine?
MediHelp also lists interactions of Colchicine with, for example, Clarithromycin, Cobicistat, Cyclosporine. The full list is on the Colchicine page.
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