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Interações medicamentosas

Cyclizine + Glycopyrrolate

Gravidade: Moderada

Cyclizine and Glycopyrrolate: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.

O que esta interação significa em palavras simples

Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cyclizine belongs to Respiratory; Glycopyrrolate belongs to Respiratory.

Nível de evidência: Moderate

Por que acontece

Additive muscarinic receptor antagonism.

O que fazer

Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Cyclizine with Glycopyrrolate?

MediHelp rates the interaction as moderate. Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.

How serious is the interaction between Cyclizine and Glycopyrrolate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.

What other medicines interact with Cyclizine?

MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.

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