Pular para o conteúdo

Interações medicamentosas

Dalteparin + Prasugrel

Gravidade: Grave

Dalteparin and Prasugrel: major interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Prasugrel is a potent P2Y12 inhibitor, and combining it with a low-molecular-weight heparin increases the risk of major bleeding. This is common in acute coronary syndrome but needs careful oversight.

O que esta interação significa em palavras simples

Dalteparin and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Dalteparin belongs to Cardiovascular; Prasugrel belongs to Cardiovascular.

Nível de evidência: High

Por que acontece

Additive effects of platelet P2Y12 blockade and antithrombin-mediated inhibition of factor Xa and thrombin.

O que fazer

Use only when clearly indicated and limit anticoagulant duration. Monitor hemoglobin, platelets and bleeding signs, and consider a gastroprotective agent.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Para assinantes do Pro+

Desbloqueie a página completa

Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Dalteparin e Prasugrel, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Experimente o Pro+ grátis por 7 dias na web. Sem cartão.

Perguntas frequentes

Can I take Dalteparin with Prasugrel?

MediHelp rates the interaction as major. Dalteparin and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Prasugrel is a potent P2Y12 inhibitor, and combining it with a low-molecular-weight heparin increases the risk of major bleeding. This is common in acute coronary syndrome but needs careful oversight.

How serious is the interaction between Dalteparin and Prasugrel?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when clearly indicated and limit anticoagulant duration. Monitor hemoglobin, platelets and bleeding signs, and consider a gastroprotective agent.

What other medicines interact with Dalteparin?

MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.

Monografias completas, posologia e verificador de interações no app MediHelp

Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.

Explorar de A a Z · Interações medicamentosas

Baixar o app Entrar