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Interações medicamentosas

Dexchlorpheniramine + Melatonin

Gravidade: Moderada

Dexchlorpheniramine and Melatonin: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Dexchlorpheniramine is a sedating antihistamine, and melatonin can add to drowsiness. Impaired alertness is possible, especially in older adults.

O que esta interação significa em palavras simples

Dexchlorpheniramine and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dexchlorpheniramine belongs to Respiratory; Melatonin belongs to Gastrointestinal Tract.

Nível de evidência: Low

Por que acontece

Additive CNS depression from H1 antagonism and melatonin receptor-mediated sedation.

O que fazer

Advise against driving or hazardous tasks until the response is known; reduce doses if excessive sedation occurs.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Dexchlorpheniramine with Melatonin?

MediHelp rates the interaction as moderate. Dexchlorpheniramine and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexchlorpheniramine is a sedating antihistamine, and melatonin can add to drowsiness. Impaired alertness is possible, especially in older adults.

How serious is the interaction between Dexchlorpheniramine and Melatonin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against driving or hazardous tasks until the response is known; reduce doses if excessive sedation occurs.

What other medicines interact with Melatonin?

MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.

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