Interações medicamentosas
Amisulpride + Dexchlorpheniramine
Gravidade: Moderada
Amisulpride and Dexchlorpheniramine: moderate interaction.
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Resumo
A first-generation antihistamine combined with amisulpride may produce more sedation and psychomotor impairment than either drug alone. Older patients are at higher risk of confusion and falls.
O que esta interação significa em palavras simples
Amisulpride and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amisulpride belongs to Central Nervous System; Dexchlorpheniramine belongs to Respiratory.
Por que acontece
Additive CNS depression from H1 antagonism and dopamine D2 antagonism.
O que fazer
Use a non-sedating antihistamine as an alternative when feasible. Counsel on drowsiness and monitor older patients for confusion.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amisulpride
- Amiodarone + Amisulpride Contraindicada
- Amisulpride + Arsenic trioxide Contraindicada
- Amisulpride + Disopyramide Contraindicada
- Amisulpride + Dofetilide Contraindicada
- Amisulpride + Droperidol Contraindicada
- Amisulpride + Ibutilide Contraindicada
Outras interações de Dexchlorpheniramine
- Alprazolam + Dexchlorpheniramine Moderada
- Amitriptyline + Dexchlorpheniramine Moderada
- Amobarbital + Dexchlorpheniramine Moderada
- Asenapine + Dexchlorpheniramine Moderada
- Azelastine-fluticasone + Dexchlorpheniramine Moderada
- Azelastine + Dexchlorpheniramine Moderada
Perguntas frequentes
Can I take Amisulpride with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Amisulpride and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. A first-generation antihistamine combined with amisulpride may produce more sedation and psychomotor impairment than either drug alone. Older patients are at higher risk of confusion and falls.
How serious is the interaction between Amisulpride and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use a non-sedating antihistamine as an alternative when feasible. Counsel on drowsiness and monitor older patients for confusion.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
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