Interações medicamentosas
Azelastine-fluticasone + Dexchlorpheniramine
Gravidade: Moderada
Azelastine-fluticasone and Dexchlorpheniramine: moderate interaction.
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Resumo
Dexchlorpheniramine is a first-generation sedating antihistamine, so combining it with azelastine duplicates therapy. This may cause additive drowsiness and anticholinergic effects.
O que esta interação significa em palavras simples
Azelastine-fluticasone and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azelastine-fluticasone belongs to Respiratory; Dexchlorpheniramine belongs to Respiratory.
Por que acontece
Additive H1-receptor antagonism and CNS depression.
O que fazer
Avoid concurrent use of two antihistamines where possible. If used together, monitor for sedation and warn about driving.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Azelastine-fluticasone
- Azelastine-fluticasone + Calcium / magnesium / potassium / sodium oxybates Grave
- Azelastine-fluticasone + Sodium oxybate Grave
- Alfentanil + Azelastine-fluticasone Moderada
- Alprazolam + Azelastine-fluticasone Moderada
- Amitriptyline + Azelastine-fluticasone Moderada
- Amobarbital + Azelastine-fluticasone Moderada
Outras interações de Dexchlorpheniramine
- Alprazolam + Dexchlorpheniramine Moderada
- Amisulpride + Dexchlorpheniramine Moderada
- Amitriptyline + Dexchlorpheniramine Moderada
- Amobarbital + Dexchlorpheniramine Moderada
- Asenapine + Dexchlorpheniramine Moderada
- Azelastine + Dexchlorpheniramine Moderada
Perguntas frequentes
Can I take Azelastine-fluticasone with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Azelastine-fluticasone and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexchlorpheniramine is a first-generation sedating antihistamine, so combining it with azelastine duplicates therapy. This may cause additive drowsiness and anticholinergic effects.
How serious is the interaction between Azelastine-fluticasone and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two antihistamines where possible. If used together, monitor for sedation and warn about driving.
What other medicines interact with Azelastine-fluticasone?
MediHelp also lists interactions of Azelastine-fluticasone with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Azelastine-fluticasone page.
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