Interações medicamentosas
Dicloxacillin + Isavuconazonium
Gravidade: Moderada
Dicloxacillin and Isavuconazonium: moderate interaction.
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Resumo
Dicloxacillin is a CYP3A4 inducer and may lower exposure to isavuconazole, the active moiety of isavuconazonium. Reduced antifungal concentrations could compromise treatment of invasive fungal infection.
O que esta interação significa em palavras simples
Dicloxacillin and Isavuconazonium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicloxacillin belongs to Anti Bacterial; Isavuconazonium belongs to Anti Fungals.
Por que acontece
Induction of CYP3A4 by dicloxacillin increases isavuconazole metabolism.
O que fazer
Monitor clinical response to antifungal therapy and consider isavuconazole trough levels if available; choose an alternative antibacterial if feasible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Dicloxacillin
- Dicloxacillin + Phenindione Grave
- Atogepant + Dicloxacillin Moderada
- Axitinib + Dicloxacillin Moderada
- Bcg vaccine live + Dicloxacillin Moderada
- Cholera vaccine + Dicloxacillin Moderada
- Demeclocycline + Dicloxacillin Moderada
Outras interações de Isavuconazonium
- Amobarbital + Isavuconazonium Contraindicada
- Apalutamide + Isavuconazonium Contraindicada
- Carbamazepine + Isavuconazonium Contraindicada
- Cisapride + Isavuconazonium Contraindicada
- Efavirenz + Isavuconazonium Contraindicada
- Enzalutamide + Isavuconazonium Contraindicada
Perguntas frequentes
Can I take Dicloxacillin with Isavuconazonium?
MediHelp rates the interaction as moderate. Dicloxacillin and Isavuconazonium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicloxacillin is a CYP3A4 inducer and may lower exposure to isavuconazole, the active moiety of isavuconazonium. Reduced antifungal concentrations could compromise treatment of invasive fungal infection.
How serious is the interaction between Dicloxacillin and Isavuconazonium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to antifungal therapy and consider isavuconazole trough levels if available; choose an alternative antibacterial if feasible.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.
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