Interações medicamentosas
Digoxin + Lily of the valley
Gravidade: Contraindicada
Digoxin and Lily of the valley: contraindicated interaction.
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Resumo
Lily of the valley (Convallaria majalis) contains cardiac glycosides such as convallatoxin. Combined with digoxin it causes additive glycoside effects and risk of digitalis toxicity with serious arrhythmias.
O que esta interação significa em palavras simples
Digoxin and Lily of the valley are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive Na+/K+-ATPase inhibition from plant cardiac glycosides and digoxin.
O que fazer
Avoid lily of the valley preparations during digoxin therapy. If ingestion occurs, obtain ECG, potassium and digoxin level and manage as glycoside toxicity.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Digoxin
- Digoxin + Squill Contraindicada
- Adagrasib + Digoxin Grave
- Amiodarone + Digoxin Grave
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Grave
- Amphotericin b deoxycholate + Digoxin Grave
- Amphotericin b + Digoxin Grave
Perguntas frequentes
Can I take Digoxin with Lily of the valley?
MediHelp rates the interaction as contraindicated. Digoxin and Lily of the valley are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lily of the valley (Convallaria majalis) contains cardiac glycosides such as convallatoxin. Combined with digoxin it causes additive glycoside effects and risk of digitalis toxicity with serious arrhythmias.
How serious is the interaction between Digoxin and Lily of the valley?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid lily of the valley preparations during digoxin therapy. If ingestion occurs, obtain ECG, potassium and digoxin level and manage as glycoside toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Squill, Adagrasib, Amiodarone. The full list is on the Digoxin page.
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