Interações medicamentosas
Digoxin + Senna
Gravidade: Moderada
Digoxin and Senna: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
O que esta interação significa em palavras simples
Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Senna belongs to Gastrointestinal Tract.
Por que acontece
Laxative-induced gastrointestinal potassium loss produces hypokalemia, which enhances digoxin's cardiac toxicity.
O que fazer
Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Digoxin
- Digoxin + Lily of the valley Contraindicada
- Digoxin + Squill Contraindicada
- Adagrasib + Digoxin Grave
- Amiodarone + Digoxin Grave
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Grave
- Amphotericin b deoxycholate + Digoxin Grave
Outras interações de Senna
Perguntas frequentes
Can I take Digoxin with Senna?
MediHelp rates the interaction as moderate. Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
How serious is the interaction between Digoxin and Senna?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
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