Interações medicamentosas
Eluxadoline + Oxymorphone
Gravidade: Grave
Eluxadoline and Oxymorphone: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Eluxadoline is used for diarrhea-predominant IBS and can cause constipation and pancreatitis-related complications. Opioids worsen constipation, raising the risk of serious constipation-related events.
O que esta interação significa em palavras simples
Eluxadoline and Oxymorphone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Eluxadoline belongs to Gastrointestinal Tract; Oxymorphone belongs to Musculoskeletal.
Por que acontece
Additive reduction in gastrointestinal motility via opioid receptor activity in the gut.
O que fazer
Avoid the combination where feasible; if constipation develops, stop eluxadoline and manage it. Monitor bowel function.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Oxymorphone
- Alvimopan + Oxymorphone Contraindicada
- Ethanol + Oxymorphone Contraindicada
- Isocarboxazid + Oxymorphone Contraindicada
- Olanzapine / samidorphan + Oxymorphone Contraindicada
- Oxymorphone + Phenelzine Contraindicada
- Oxymorphone + Selegiline transdermal Contraindicada
Outras interações de Eluxadoline
Perguntas frequentes
Can I take Eluxadoline with Oxymorphone?
MediHelp rates the interaction as major. Eluxadoline and Oxymorphone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eluxadoline is used for diarrhea-predominant IBS and can cause constipation and pancreatitis-related complications. Opioids worsen constipation, raising the risk of serious constipation-related events.
How serious is the interaction between Eluxadoline and Oxymorphone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where feasible; if constipation develops, stop eluxadoline and manage it. Monitor bowel function.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
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