Interações medicamentosas
Etoposide + Pentostatin
Gravidade: Contraindicada
Etoposide and Pentostatin: contraindicated interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
In high-dose transplant conditioning with carmustine and cyclophosphamide, pentostatin was linked to fatal pulmonary edema and hypotension. Use together in this setting is dangerous.
O que esta interação significa em palavras simples
Etoposide and Pentostatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Etoposide belongs to Oncology; Pentostatin belongs to Oncology.
Por que acontece
Mechanism not established; additive pulmonary and cardiovascular toxicity is suspected.
O que fazer
Avoid pentostatin with high-dose etoposide-containing ablative regimens and choose a different conditioning approach.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Pentostatin
- Carmustine + Pentostatin Contraindicada
- Fludarabine + Pentostatin Contraindicada
- Cyclophosphamide + Pentostatin Grave
- Deferiprone + Pentostatin Grave
- Fingolimod + Pentostatin Grave
- Nelarabine + Pentostatin Grave
Outras interações de Etoposide
Perguntas frequentes
Can I take Etoposide with Pentostatin?
MediHelp rates the interaction as contraindicated. Etoposide and Pentostatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. In high-dose transplant conditioning with carmustine and cyclophosphamide, pentostatin was linked to fatal pulmonary edema and hypotension. Use together in this setting is dangerous.
How serious is the interaction between Etoposide and Pentostatin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid pentostatin with high-dose etoposide-containing ablative regimens and choose a different conditioning approach.
What other medicines interact with Pentostatin?
MediHelp also lists interactions of Pentostatin with, for example, Carmustine, Fludarabine, Cyclophosphamide. The full list is on the Pentostatin page.
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