Interações medicamentosas
Ferrous fumarate + Trientine
Gravidade: Moderada
Ferrous fumarate and Trientine: moderate interaction.
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Resumo
Oral iron and trientine chelate each other in the gut, so both iron absorption and trientine's copper-lowering effect may fall. Iron-trientine complexes are also poorly absorbed and can be toxic to the gut.
O que esta interação significa em palavras simples
Ferrous fumarate and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous fumarate belongs to Miscellaneous; Trientine belongs to Miscellaneous.
Por que acontece
Trientine chelates iron in the gastrointestinal tract, forming poorly absorbed complexes that reduce absorption of both agents.
O que fazer
Give iron at least 2 hours apart from trientine. Monitor copper indices in Wilson disease and iron indices in the patient.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ferrous fumarate
Outras interações de Trientine
- Calcium + Trientine Moderada
- Carbonyl iron + Trientine Moderada
- Copper + Trientine Moderada
- Ferrous gluconate + Trientine Moderada
- Ferrous sulfate + Trientine Moderada
- Iron + Trientine Moderada
Perguntas frequentes
Can I take Ferrous fumarate with Trientine?
MediHelp rates the interaction as moderate. Ferrous fumarate and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron and trientine chelate each other in the gut, so both iron absorption and trientine's copper-lowering effect may fall. Iron-trientine complexes are also poorly absorbed and can be toxic to the gut.
How serious is the interaction between Ferrous fumarate and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give iron at least 2 hours apart from trientine. Monitor copper indices in Wilson disease and iron indices in the patient.
What other medicines interact with Ferrous fumarate?
MediHelp also lists interactions of Ferrous fumarate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous fumarate page.
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