Interações medicamentosas
Carbonyl iron + Trientine
Gravidade: Moderada
Carbonyl iron and Trientine: moderate interaction.
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Resumo
Oral iron and trientine chelate each other in the gut, reducing absorption of both and possibly weakening copper removal in Wilson disease. Iron-trientine complexes may also irritate the gut.
O que esta interação significa em palavras simples
Carbonyl iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Trientine belongs to Miscellaneous.
Por que acontece
Trientine chelates iron in the gastrointestinal tract, forming poorly absorbed complexes.
O que fazer
Give iron at least 2 hours apart from trientine. Monitor copper and iron indices.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderada
- Baloxavir marboxil + Carbonyl iron Moderada
- Calcium acetate + Carbonyl iron Moderada
- Calcium carbonate + Carbonyl iron Moderada
- Calcium + Carbonyl iron Moderada
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderada
Outras interações de Trientine
- Calcium + Trientine Moderada
- Copper + Trientine Moderada
- Ferrous fumarate + Trientine Moderada
- Ferrous gluconate + Trientine Moderada
- Ferrous sulfate + Trientine Moderada
- Iron + Trientine Moderada
Perguntas frequentes
Can I take Carbonyl iron with Trientine?
MediHelp rates the interaction as moderate. Carbonyl iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron and trientine chelate each other in the gut, reducing absorption of both and possibly weakening copper removal in Wilson disease. Iron-trientine complexes may also irritate the gut.
How serious is the interaction between Carbonyl iron and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give iron at least 2 hours apart from trientine. Monitor copper and iron indices.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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