Interações medicamentosas
Ferrous sulfate + Trientine
Gravidade: Moderada
Ferrous sulfate and Trientine: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Iron and trientine chelate each other in the gut, reducing absorption of both. Trientine efficacy in copper removal may drop, and the iron may be less effective as well.
O que esta interação significa em palavras simples
Ferrous sulfate and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous sulfate belongs to Miscellaneous; Trientine belongs to Miscellaneous.
Por que acontece
Mutual chelation in the gastrointestinal tract forms poorly absorbed complexes.
O que fazer
Separate iron and trientine by at least 2 hours. Monitor copper indices in Wilson disease and iron indices.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ferrous sulfate
Outras interações de Trientine
- Calcium + Trientine Moderada
- Carbonyl iron + Trientine Moderada
- Copper + Trientine Moderada
- Ferrous fumarate + Trientine Moderada
- Ferrous gluconate + Trientine Moderada
- Iron + Trientine Moderada
Perguntas frequentes
Can I take Ferrous sulfate with Trientine?
MediHelp rates the interaction as moderate. Ferrous sulfate and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron and trientine chelate each other in the gut, reducing absorption of both. Trientine efficacy in copper removal may drop, and the iron may be less effective as well.
How serious is the interaction between Ferrous sulfate and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate iron and trientine by at least 2 hours. Monitor copper indices in Wilson disease and iron indices.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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