Interações medicamentosas
Iron + Trientine
Gravidade: Moderada
Iron and Trientine: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Trientine chelates iron in the gut, lowering absorption of both trientine and iron. Iron deficiency can result, and trientine efficacy in Wilson disease may be reduced.
O que esta interação significa em palavras simples
Iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iron belongs to Gastrointestinal Tract; Trientine belongs to Miscellaneous.
Por que acontece
Chelation of iron by trientine in the gastrointestinal tract forms poorly absorbed complexes.
O que fazer
Separate oral iron from trientine by at least 2 hours. Monitor iron indices and copper control during combined therapy.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Iron
- Acetohydroxamic acid + Iron Moderada
- Aluminum hydroxide + Iron Moderada
- Baloxavir marboxil + Iron Moderada
- Calcium acetate + Iron Moderada
- Calcium carbonate + Iron Moderada
- Calcium citrate + Iron Moderada
Outras interações de Trientine
- Calcium + Trientine Moderada
- Carbonyl iron + Trientine Moderada
- Copper + Trientine Moderada
- Ferrous fumarate + Trientine Moderada
- Ferrous gluconate + Trientine Moderada
- Ferrous sulfate + Trientine Moderada
Perguntas frequentes
Can I take Iron with Trientine?
MediHelp rates the interaction as moderate. Iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Trientine chelates iron in the gut, lowering absorption of both trientine and iron. Iron deficiency can result, and trientine efficacy in Wilson disease may be reduced.
How serious is the interaction between Iron and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral iron from trientine by at least 2 hours. Monitor iron indices and copper control during combined therapy.
What other medicines interact with Iron?
MediHelp also lists interactions of Iron with, for example, Acetohydroxamic acid, Aluminum hydroxide, Baloxavir marboxil. The full list is on the Iron page.
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