Interações medicamentosas
Fluvastatin + Niacin
Gravidade: Moderada
Fluvastatin and Niacin: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Lipid-modifying doses of niacin given with a statin may add to the risk of myopathy and rarely rhabdomyolysis. The risk appears greatest at high niacin doses and in patients with renal impairment or advanced age.
O que esta interação significa em palavras simples
Fluvastatin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluvastatin belongs to Cardiovascular; Niacin belongs to Cardiovascular.
Por que acontece
Additive myotoxicity; niacin may also contribute to muscle injury through an unclear mechanism.
O que fazer
Use the lowest effective doses and educate the patient to report muscle pain, weakness or dark urine. Check CK and renal function if symptoms develop.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Fluvastatin
- Cyclosporine + Fluvastatin Grave
- Cyclosporin + Fluvastatin Grave
- Fluvastatin + Gemfibrozil Grave
- Fluvastatin + Letermovir Grave
- Fluvastatin + Red yeast rice Grave
- Apalutamide + Fluvastatin Moderada
Outras interações de Niacin
- Alogliptin-metformin + Niacin Moderada
- Atorvastatin + Niacin Moderada
- Canagliflozin-metformin + Niacin Moderada
- Cholestyramine + Niacin Moderada
- Colestipol + Niacin Moderada
- Dapagliflozin-metformin + Niacin Moderada
Perguntas frequentes
Can I take Fluvastatin with Niacin?
MediHelp rates the interaction as moderate. Fluvastatin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lipid-modifying doses of niacin given with a statin may add to the risk of myopathy and rarely rhabdomyolysis. The risk appears greatest at high niacin doses and in patients with renal impairment or advanced age.
How serious is the interaction between Fluvastatin and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and educate the patient to report muscle pain, weakness or dark urine. Check CK and renal function if symptoms develop.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporine, Cyclosporin, Gemfibrozil. The full list is on the Fluvastatin page.
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