Interações medicamentosas
Fluvastatin + Vitamin b3
Gravidade: Moderada
Fluvastatin and Vitamin b3: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Lipid-lowering doses of niacin combined with a statin may increase the risk of myopathy and rarely rhabdomyolysis. The risk appears greatest at higher niacin doses and in patients with renal impairment or older age.
O que esta interação significa em palavras simples
Fluvastatin and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluvastatin belongs to Cardiovascular; Vitamin b3 belongs to Gastrointestinal Tract.
Por que acontece
Additive myotoxicity; the mechanism is not fully established.
O que fazer
Use the lowest effective doses and counsel patients to report unexplained muscle pain or weakness. Check CK if symptoms occur and stop therapy if myopathy is suspected.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Fluvastatin e Vitamin b3, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Vitamin b3
- Lovastatin + Vitamin b3 Grave
- Simvastatin + Vitamin b3 Grave
- Atorvastatin + Vitamin b3 Moderada
- Cholestyramine + Vitamin b3 Moderada
- Colestipol + Vitamin b3 Moderada
- Insulin aspart protamine / insulin aspart + Vitamin b3 Moderada
Outras interações de Fluvastatin
- Cyclosporine + Fluvastatin Grave
- Cyclosporin + Fluvastatin Grave
- Fluvastatin + Gemfibrozil Grave
- Fluvastatin + Letermovir Grave
- Fluvastatin + Red yeast rice Grave
- Apalutamide + Fluvastatin Moderada
Perguntas frequentes
Can I take Fluvastatin with Vitamin b3?
MediHelp rates the interaction as moderate. Fluvastatin and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lipid-lowering doses of niacin combined with a statin may increase the risk of myopathy and rarely rhabdomyolysis. The risk appears greatest at higher niacin doses and in patients with renal impairment or older age.
How serious is the interaction between Fluvastatin and Vitamin b3?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and counsel patients to report unexplained muscle pain or weakness. Check CK if symptoms occur and stop therapy if myopathy is suspected.
What other medicines interact with Vitamin b3?
MediHelp also lists interactions of Vitamin b3 with, for example, Lovastatin, Simvastatin, Atorvastatin. The full list is on the Vitamin b3 page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
