Interações medicamentosas
Folic acid + Pafolacianine
Gravidade: Moderada
Folic acid and Pafolacianine: moderate interaction.
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Resumo
Pafolacianine is an optical imaging agent that targets folate receptors on ovarian cancer cells. Folic acid competes for these receptors and may reduce tumor uptake, causing lesions to be missed during surgery.
O que esta interação significa em palavras simples
Folic acid and Pafolacianine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Competitive binding at folate receptors reduces pafolacianine uptake.
O que fazer
Withhold folic acid and folate-containing supplements for at least 48 hours before pafolacianine administration.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Folic acid
- Ethotoin + Folic acid Moderada
- Folic acid + Fosphenytoin Moderada
- Folic acid + Glucarpidase Moderada
- Folic acid + Methotrexate Moderada
- Folic acid + Phenobarbital Moderada
- Folic acid + Phenytoin Moderada
Perguntas frequentes
Can I take Folic acid with Pafolacianine?
MediHelp rates the interaction as moderate. Folic acid and Pafolacianine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pafolacianine is an optical imaging agent that targets folate receptors on ovarian cancer cells. Folic acid competes for these receptors and may reduce tumor uptake, causing lesions to be missed during surgery.
How serious is the interaction between Folic acid and Pafolacianine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold folic acid and folate-containing supplements for at least 48 hours before pafolacianine administration.
What other medicines interact with Folic acid?
MediHelp also lists interactions of Folic acid with, for example, Ethotoin, Fosphenytoin, Glucarpidase. The full list is on the Folic acid page.
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