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Interações medicamentosas

Golimumab + Measles mumps rubella and varicella vaccine live

Gravidade: Contraindicada

Golimumab and Measles mumps rubella and varicella vaccine live: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

This live attenuated combination vaccine could cause disseminated vaccine-strain infection in patients immunosuppressed by golimumab, and the immune response may be diminished.

O que esta interação significa em palavras simples

Golimumab and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

TNF-alpha blockade impairs immune control of replicating live attenuated viruses.

O que fazer

Avoid during golimumab therapy; vaccinate at least 4 weeks before starting if possible and follow guidelines for timing after stopping.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Golimumab with Measles mumps rubella and varicella vaccine live?

MediHelp rates the interaction as contraindicated. Golimumab and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine could cause disseminated vaccine-strain infection in patients immunosuppressed by golimumab, and the immune response may be diminished.

How serious is the interaction between Golimumab and Measles mumps rubella and varicella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during golimumab therapy; vaccinate at least 4 weeks before starting if possible and follow guidelines for timing after stopping.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

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