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Interações medicamentosas

Bcg vaccine live + Golimumab

Gravidade: Contraindicada

Bcg vaccine live and Golimumab: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

BCG vaccine contains live attenuated mycobacteria. In golimumab-treated patients, impaired granuloma function may allow disseminated BCG infection.

O que esta interação significa em palavras simples

Bcg vaccine live and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

TNF is essential for granuloma formation and mycobacterial containment, so its blockade permits BCG dissemination.

O que fazer

Do not give BCG during golimumab therapy. If needed, vaccinate at least 4 weeks before starting treatment.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

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Perguntas frequentes

Can I take Bcg vaccine live with Golimumab?

MediHelp rates the interaction as contraindicated. Bcg vaccine live and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG vaccine contains live attenuated mycobacteria. In golimumab-treated patients, impaired granuloma function may allow disseminated BCG infection.

How serious is the interaction between Bcg vaccine live and Golimumab?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during golimumab therapy. If needed, vaccinate at least 4 weeks before starting treatment.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Etanercept, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Golimumab page.

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