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Interações medicamentosas

Golimumab + Measles vaccine

Gravidade: Contraindicada

Golimumab and Measles vaccine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.

O que esta interação significa em palavras simples

Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

TNF-alpha blockade impairs immune control of replicating live attenuated virus.

O que fazer

Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Golimumab with Measles vaccine?

MediHelp rates the interaction as contraindicated. Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.

How serious is the interaction between Golimumab and Measles vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

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