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Interações medicamentosas

Golimumab + Measles mumps and rubella vaccine

Gravidade: Contraindicada

Golimumab and Measles mumps and rubella vaccine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Golimumab is a TNF-alpha antagonist, which weakens the control of live attenuated measles, mumps, rubella and varicella viruses. Disseminated vaccine-strain infection can occur and the vaccine response is also reduced.

O que esta interação significa em palavras simples

Golimumab and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Golimumab belongs to Musculoskeletal; Measles mumps and rubella vaccine belongs to Miscellaneous.

Nível de evidência: High

Por que acontece

Immunosuppression permits replication of live attenuated vaccine viruses: TNF-alpha blockade impairing immune responses

O que fazer

Do not give live vaccines during treatment; vaccinate at least 4 weeks before starting, and wait the interval recommended in the product labelling (commonly about 3 months or more) after stopping.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Golimumab with Measles mumps and rubella vaccine?

MediHelp rates the interaction as contraindicated. Golimumab and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Golimumab is a TNF-alpha antagonist, which weakens the control of live attenuated measles, mumps, rubella and varicella viruses. Disseminated vaccine-strain infection can occur and the vaccine response is also reduced.

How serious is the interaction between Golimumab and Measles mumps and rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment; vaccinate at least 4 weeks before starting, and wait the interval recommended in the product labelling (commonly about 3 months or more) after stopping.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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