Interações medicamentosas
Itraconazole + Nizatidine
Gravidade: Grave
Itraconazole and Nizatidine: major interaction.
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Resumo
Itraconazole capsules need gastric acid for absorption, and nizatidine lowers acidity. Reduced itraconazole levels may cause antifungal treatment failure.
O que esta interação significa em palavras simples
Itraconazole and Nizatidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Itraconazole belongs to Anti Fungals; Nizatidine belongs to Gastrointestinal Tract.
Por que acontece
Reduced acid-dependent dissolution and absorption of itraconazole capsules.
O que fazer
Avoid with itraconazole capsules, or use the oral solution or SUBA formulation, which is less dependent on acid. Monitor itraconazole levels and clinical response.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Nizatidine
- Atazanavir + Nizatidine Grave
- Dasatinib + Nizatidine Grave
- Erlotinib + Nizatidine Grave
- Ketoconazole + Nizatidine Grave
- Nizatidine + Pazopanib Grave
- Nizatidine + Rilpivirine Grave
Outras interações de Itraconazole
- Alfuzosin + Itraconazole Contraindicada
- Alprazolam + Itraconazole Contraindicada
- Avanafil + Itraconazole Contraindicada
- Conivaptan + Itraconazole Contraindicada
- Dihydroergotamine intranasal + Itraconazole Contraindicada
- Dihydroergotamine + Itraconazole Contraindicada
Perguntas frequentes
Can I take Itraconazole with Nizatidine?
MediHelp rates the interaction as major. Itraconazole and Nizatidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Itraconazole capsules need gastric acid for absorption, and nizatidine lowers acidity. Reduced itraconazole levels may cause antifungal treatment failure.
How serious is the interaction between Itraconazole and Nizatidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with itraconazole capsules, or use the oral solution or SUBA formulation, which is less dependent on acid. Monitor itraconazole levels and clinical response.
What other medicines interact with Nizatidine?
MediHelp also lists interactions of Nizatidine with, for example, Atazanavir, Dasatinib, Erlotinib. The full list is on the Nizatidine page.
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