Interações medicamentosas
Linezolid + Ozanimod
Gravidade: Contraindicada
Linezolid and Ozanimod: contraindicated interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.
O que esta interação significa em palavras simples
Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Linezolid belongs to Anti Bacterial; Ozanimod belongs to Central Nervous System.
Por que acontece
Additive MAO inhibition and altered ozanimod metabolite exposure.
O que fazer
Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Linezolid
- Amoxapine + Linezolid Contraindicada
- Atomoxetine + Linezolid Contraindicada
- Benzphetamine + Linezolid Contraindicada
- Brimonidine + Linezolid Contraindicada
- Bupropion-naltrexone + Linezolid Contraindicada
- Bupropion + Linezolid Contraindicada
Outras interações de Ozanimod
- Isocarboxazid + Ozanimod Contraindicada
- Ozanimod + Phenelzine Contraindicada
- Ozanimod + Procarbazine Contraindicada
- Ozanimod + Rasagiline Contraindicada
- Ozanimod + Safinamide Contraindicada
- Ozanimod + Tranylcypromine Contraindicada
Perguntas frequentes
Can I take Linezolid with Ozanimod?
MediHelp rates the interaction as contraindicated. Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.
How serious is the interaction between Linezolid and Ozanimod?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
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