Interações medicamentosas
Ozanimod + Phenelzine
Gravidade: Contraindicada
Ozanimod and Phenelzine: contraindicated interaction.
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Resumo
Ozanimod has active metabolites that inhibit MAO-B, and concurrent nonselective MAO inhibition may lead to hypertensive crisis or serotonin syndrome. The interaction has not been formally studied, but labeling contraindicates the combination.
O que esta interação significa em palavras simples
Ozanimod and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ozanimod belongs to Central Nervous System; Phenelzine belongs to Central Nervous System.
Por que acontece
Ozanimod's active metabolites inhibit MAO-B, which adds to nonselective MAO inhibition and may impair catecholamine and serotonin metabolism.
O que fazer
Avoid concurrent use. Allow at least 14 days between stopping either drug and starting the other.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Phenelzine
- 5-HTP + Phenelzine Contraindicada
- Amitriptyline + Phenelzine Contraindicada
- Amoxapine + Phenelzine Contraindicada
- Atomoxetine + Phenelzine Contraindicada
- Benzphetamine + Phenelzine Contraindicada
- Brimonidine + Phenelzine Contraindicada
Outras interações de Ozanimod
- Isocarboxazid + Ozanimod Contraindicada
- Linezolid + Ozanimod Contraindicada
- Ozanimod + Procarbazine Contraindicada
- Ozanimod + Rasagiline Contraindicada
- Ozanimod + Safinamide Contraindicada
- Ozanimod + Tranylcypromine Contraindicada
Perguntas frequentes
Can I take Ozanimod with Phenelzine?
MediHelp rates the interaction as contraindicated. Ozanimod and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod has active metabolites that inhibit MAO-B, and concurrent nonselective MAO inhibition may lead to hypertensive crisis or serotonin syndrome. The interaction has not been formally studied, but labeling contraindicates the combination.
How serious is the interaction between Ozanimod and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use. Allow at least 14 days between stopping either drug and starting the other.
What other medicines interact with Phenelzine?
MediHelp also lists interactions of Phenelzine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Phenelzine page.
Monografias completas, posologia e verificador de interações no app MediHelp
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