Interações medicamentosas
Measles mumps and rubella vaccine + Sirolimus
Gravidade: Contraindicada
Measles mumps and rubella vaccine and Sirolimus: contraindicated interaction.
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Resumo
Sirolimus is a potent immunosuppressant used in transplantation. It may reduce vaccine response and allow the live vaccine viruses to replicate, raising the risk of vaccine-strain infection.
O que esta interação significa em palavras simples
Measles mumps and rubella vaccine and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Sirolimus belongs to Miscellaneous.
Por que acontece
mTOR inhibition suppresses T-cell proliferation, impairing control of live attenuated virus.
O que fazer
Avoid live vaccines during sirolimus therapy. Give MMR before transplant or immunosuppression where possible.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicada
- Anakinra + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicada
- Azathioprine + Measles mumps and rubella vaccine Contraindicada
- Basiliximab + Measles mumps and rubella vaccine Contraindicada
Outras interações de Sirolimus
- Adenovirus types 4 and 7 live + Sirolimus Contraindicada
- Bcg vaccine live + Sirolimus Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Sirolimus Contraindicada
- Ketoconazole + Sirolimus Contraindicada
- Levoketoconazole + Sirolimus Contraindicada
- Measles mumps and rubella vaccine live + Sirolimus Contraindicada
Perguntas frequentes
Can I take Measles mumps and rubella vaccine with Sirolimus?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Sirolimus is a potent immunosuppressant used in transplantation. It may reduce vaccine response and allow the live vaccine viruses to replicate, raising the risk of vaccine-strain infection.
How serious is the interaction between Measles mumps and rubella vaccine and Sirolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during sirolimus therapy. Give MMR before transplant or immunosuppression where possible.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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