Interações medicamentosas
Measles mumps and rubella vaccine live + Sirolimus
Gravidade: Contraindicada
Measles mumps and rubella vaccine live and Sirolimus: contraindicated interaction.
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O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
The live MMR vaccine may cause disseminated vaccine-strain infection in patients immunosuppressed with sirolimus, and immunogenicity may be poor.
O que esta interação significa em palavras simples
Measles mumps and rubella vaccine live and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Sirolimus immunosuppression permits replication of live attenuated viruses and blunts vaccine response.
O que fazer
Do not administer during sirolimus therapy. Immunize before transplant or immunosuppression, and check immunity serologically.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Sirolimus
- Adenovirus types 4 and 7 live + Sirolimus Contraindicada
- Bcg vaccine live + Sirolimus Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Sirolimus Contraindicada
- Ketoconazole + Sirolimus Contraindicada
- Levoketoconazole + Sirolimus Contraindicada
- Measles mumps and rubella vaccine + Sirolimus Contraindicada
Perguntas frequentes
Can I take Measles mumps and rubella vaccine live with Sirolimus?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine live and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live MMR vaccine may cause disseminated vaccine-strain infection in patients immunosuppressed with sirolimus, and immunogenicity may be poor.
How serious is the interaction between Measles mumps and rubella vaccine live and Sirolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during sirolimus therapy. Immunize before transplant or immunosuppression, and check immunity serologically.
What other medicines interact with Sirolimus?
MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Sirolimus page.
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