Interações medicamentosas
Moxifloxacin + Pentamidine
Gravidade: Contraindicada
Moxifloxacin and Pentamidine: contraindicated interaction.
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Resumo
Both agents can prolong the QT interval, and pentamidine has been associated with torsades de pointes. Together they increase the chance of life-threatening ventricular arrhythmia.
O que esta interação significa em palavras simples
Moxifloxacin and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Moxifloxacin belongs to Anti Bacterial; Pentamidine belongs to Anti Parasitic.
Por que acontece
Additive QT prolongation through effects on cardiac repolarization currents.
O que fazer
Avoid the combination and select a non-QT-prolonging antibiotic. If pentamidine is essential, obtain baseline and follow-up ECGs and correct potassium and magnesium.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicada
- Arsenic trioxide + Moxifloxacin Contraindicada
- Disopyramide + Moxifloxacin Contraindicada
- Dofetilide + Moxifloxacin Contraindicada
- Dronedarone + Moxifloxacin Contraindicada
- Droperidol + Moxifloxacin Contraindicada
Outras interações de Pentamidine
- Clomipramine + Pentamidine Contraindicada
- Desipramine + Pentamidine Contraindicada
- Dronedarone + Pentamidine Contraindicada
- Nortriptyline + Pentamidine Contraindicada
- Pentamidine + Pimozide Contraindicada
- Pentamidine + Thioridazine Contraindicada
Perguntas frequentes
Can I take Moxifloxacin with Pentamidine?
MediHelp rates the interaction as contraindicated. Moxifloxacin and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents can prolong the QT interval, and pentamidine has been associated with torsades de pointes. Together they increase the chance of life-threatening ventricular arrhythmia.
How serious is the interaction between Moxifloxacin and Pentamidine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and select a non-QT-prolonging antibiotic. If pentamidine is essential, obtain baseline and follow-up ECGs and correct potassium and magnesium.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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