Interações medicamentosas
Clomipramine + Pentamidine
Gravidade: Contraindicada
Clomipramine and Pentamidine: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Both drugs can prolong the QT interval, and systemic pentamidine has been associated with torsades de pointes. Combined use raises the risk of life-threatening ventricular arrhythmia.
O que esta interação significa em palavras simples
Clomipramine and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Clomipramine belongs to Central Nervous System; Pentamidine belongs to Anti Parasitic.
Por que acontece
Additive prolongation of cardiac repolarization through effects on cardiac ion channels.
O que fazer
Avoid concurrent use; choose a non-QT-prolonging alternative for one of the drugs. If pentamidine is essential, withhold clomipramine where feasible and monitor ECG and electrolytes.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Clomipramine e Pentamidine, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Clomipramine
- Arsenic trioxide + Clomipramine Contraindicada
- Clomipramine + Dofetilide Contraindicada
- Clomipramine + Droperidol Contraindicada
- Clomipramine + Isocarboxazid Contraindicada
- Clomipramine + Methylene blue Contraindicada
- Clomipramine + Phenelzine Contraindicada
Outras interações de Pentamidine
- Desipramine + Pentamidine Contraindicada
- Dronedarone + Pentamidine Contraindicada
- Moxifloxacin + Pentamidine Contraindicada
- Nortriptyline + Pentamidine Contraindicada
- Pentamidine + Pimozide Contraindicada
- Pentamidine + Thioridazine Contraindicada
Perguntas frequentes
Can I take Clomipramine with Pentamidine?
MediHelp rates the interaction as contraindicated. Clomipramine and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs can prolong the QT interval, and systemic pentamidine has been associated with torsades de pointes. Combined use raises the risk of life-threatening ventricular arrhythmia.
How serious is the interaction between Clomipramine and Pentamidine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; choose a non-QT-prolonging alternative for one of the drugs. If pentamidine is essential, withhold clomipramine where feasible and monitor ECG and electrolytes.
What other medicines interact with Clomipramine?
MediHelp also lists interactions of Clomipramine with, for example, Arsenic trioxide, Dofetilide, Droperidol. The full list is on the Clomipramine page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
