藥品參考
Aztreonam
Aztreonam is a medicine in the class anti bacterial. It is used for cystic fibrosis.
- 藥物類別: Anti Bacterial
- 用途: cystic fibrosis
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- ATC 代碼
- J01DF01
- 常見劑型
- 注射劑
- 常見規格
- 1 g, 500 mg
- 已知交互作用
- 16 (中度: 5 · 輕微: 11)
- 商品名
- 5
- 國家與市場
- 3
用途
作用方式
Monobactam; inhibits cell wall synthesis by binding to penicillin binding proteins
成人常用劑量（仿單摘要）
Systemic Infections (Moderately severe): 1-2 g IV/IM q8-12hr; not to exceed 8 g/day
懷孕與哺乳
- 懷孕
- Safe Crosses the placenta; animal studies showed no harm and limited human use has not shown problems. As a beta-lactam it is an acceptable option when a serious gram-negative infection needs treatment.
- 哺乳
- Safe Milk levels are under 1% of maternal blood levels and it is poorly absorbed from the infant gut. US label suggests considering a temporary pause; LactMed: acceptable. Watch for diarrhoea or thrush. Inhaled aztreonam gives even lower exposure.
已通報的副作用
- Cough
- Fever
- Nasal congestion
- Sore throat
- Wheezing
哪些人需要特別留意
- May cause bronchospasm, stop treatment if chest tightness develops during nebulizer use
- In patients with impaired hepatic or renal function, appropriate monitoring is recommended during therapy
- If aminoglycoside is used concurrently, especially if high dosages of former are used or if therapy is prolonged, renal function should be monitored
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (16)
- Aztreonam + Cefoxitin Moderate
- Aztreonam + Cholera vaccine Moderate
- Aztreonam + Microbiota Moderate
- Aztreonam + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderate
- Aztreonam + Typhoid vaccine live Moderate
- Amikacin + Aztreonam Minor
- Amoxicillin + Aztreonam Minor
- Amoxicillin-clavulanic acid + Aztreonam Minor
- Aztreonam + Bcg vaccine live Minor
- Aztreonam + Cefpirome Minor
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Aztreonam 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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常見問題
What is Aztreonam used for?
Aztreonam is a medicine in the class anti bacterial. It is used for Cystic fibrosis, Pseudomonal infections, Sepsis, Urinary tract infections.
What side effects have been reported with Aztreonam?
Cough, Fever, Nasal congestion, Sore throat, Wheezing.
Can Aztreonam be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Crosses the placenta; animal studies showed no harm and limited human use has not shown problems. As a beta-lactam it is an acceptable option when a serious gram-negative infection needs treatment. Breastfeeding: Safe. Milk levels are under 1% of maternal blood levels and it is poorly absorbed from the infant gut. US label suggests considering a temporary pause; LactMed: acceptable. Watch for diarrhoea or thrush. Inhaled aztreonam gives even lower exposure.
What does Aztreonam interact with?
MediHelp lists 16 known interactions for Aztreonam. Moderate: 5 · Minor: 11. The most serious include Cefoxitin, Cholera vaccine, Microbiota.
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