藥物交互作用
Aztreonam + Typhoid vaccine live
嚴重程度: 中度
Aztreonam and Typhoid vaccine live: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi in the gut. Aztreonam is active against gram-negative bacilli including Salmonella and could reduce vaccine viability and immune response.
用白話說明這項交互作用的意義
Aztreonam and Typhoid vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity may inhibit the live attenuated Salmonella strain, reducing immunogenicity.
處置方式
Give live oral typhoid vaccine at least 3 days after the last aztreonam dose, or vaccinate beforehand. Use the inactivated Vi vaccine if timing cannot be separated.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aztreonam 的其他交互作用
常見問題
Can I take Aztreonam with Typhoid vaccine live?
MediHelp rates the interaction as moderate. Aztreonam and Typhoid vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi in the gut. Aztreonam is active against gram-negative bacilli including Salmonella and could reduce vaccine viability and immune response.
How serious is the interaction between Aztreonam and Typhoid vaccine live?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give live oral typhoid vaccine at least 3 days after the last aztreonam dose, or vaccinate beforehand. Use the inactivated Vi vaccine if timing cannot be separated.
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
