藥物交互作用
Aztreonam + Sodium picosulfate / magnesium oxide / anhydrous citric acid
嚴重程度: 中度
Aztreonam and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
最後更新
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摘要
Sodium picosulfate is a prodrug that needs colonic bacteria to convert it into its active laxative form. Antibacterial agents that reduce colonic flora could weaken the bowel-cleansing effect before colonoscopy. Aztreonam has activity against gram-negative aerobes, and the label for the preparation warns about antibiotic use.
用白話說明這項交互作用的意義
Aztreonam and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibiotic-induced reduction of colonic bacteria impairs conversion of sodium picosulfate to its active metabolite.
處置方式
Be alert to inadequate bowel preparation in patients receiving the antibiotic and consider extra preparation or rescheduling if cleansing is poor. Where clinically possible, avoid starting the antibiotic course during the preparation window.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aztreonam 的其他交互作用
常見問題
Can I take Aztreonam with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Aztreonam and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that needs colonic bacteria to convert it into its active laxative form. Antibacterial agents that reduce colonic flora could weaken the bowel-cleansing effect before colonoscopy. Aztreonam has activity against gram-negative aerobes, and the label for the preparation warns about antibiotic use.
How serious is the interaction between Aztreonam and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be alert to inadequate bowel preparation in patients receiving the antibiotic and consider extra preparation or rescheduling if cleansing is poor. Where clinically possible, avoid starting the antibiotic course during the preparation window.
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
