藥品參考
Carbimazole
Carbimazole is a medicine in the class endocrine. It is used for hyperthyroidism.
- 藥物類別: Endocrine
- 用途: hyperthyroidism
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重點資訊
- 藥物類別
- Endocrine
- 常見劑型
- 錠劑
- 常見規格
- 5 mg, 20 mg
- 已知交互作用
- 2 (中度: 2)
- 商品名
- 10
- 國家與市場
- 4
用途
作用方式
Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis. Carbimazole is an aitithyroid agent that decreases the uptake and concentration of inorganic iodine by thyroid, it also reduces the formation of di-iodotyrosine and thyroxine.
成人常用劑量（仿單摘要）
Initial dose is in the range 20 mg to 60 mg, taken as two to three divided doses.
懷孕與哺乳
- 懷孕
- Unsafe Suspected to cause birth defects with 1st-trimester use (scalp, gut and abdominal wall defects). Use effective contraception; in early pregnancy propylthiouracil is usually preferred. If needed later, use the lowest dose and monitor mother, fetus and newborn thyroid.
- 哺乳
- Safe Converted to methimazole, which passes into milk. UK label: do not breastfeed if treatment continues. LactMed and thyroid guidelines: moderate doses are acceptable and do not affect infant thyroid function; monitor infant growth.
已通報的副作用
- Headache
- Nausea
- Angioedema
- Bone marrow depression
- Acute pancreatitis
哪些人需要特別留意
- Patients unable to comply with the instructions for use or who cannot be monitored regularly should not be treated with carbimazole.
- Carbimazole tablets should be used with caution in patients with mild-moderate hepatic insufficiency.
- Precaution should be taken in patients with intrathoracic goitre, which may worsen during initial treatment with carbimazole
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (2)
- Carbimazole + Rosuvastatin Moderate
- Carbimazole + Tiratricol Moderate
同類別的其他藥品
常見問題
What is Carbimazole used for?
Carbimazole is a medicine in the class endocrine. It is used for Hyperthyroidism.
What side effects have been reported with Carbimazole?
Headache, Nausea, Angioedema, Bone marrow depression, Acute pancreatitis.
Can Carbimazole be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Suspected to cause birth defects with 1st-trimester use (scalp, gut and abdominal wall defects). Use effective contraception; in early pregnancy propylthiouracil is usually preferred. If needed later, use the lowest dose and monitor mother, fetus and newborn thyroid. Breastfeeding: Safe. Converted to methimazole, which passes into milk. UK label: do not breastfeed if treatment continues. LactMed and thyroid guidelines: moderate doses are acceptable and do not affect infant thyroid function; monitor infant growth.
What does Carbimazole interact with?
MediHelp lists 2 known interactions for Carbimazole. Moderate: 2. The most serious include Rosuvastatin, Tiratricol.
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