藥品參考
Liothyronine
Liothyronine is a medicine in the class endocrine. It is used for hypothyroidism.
- 藥物類別: Endocrine
- 用途: hypothyroidism
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Endocrine
- 常見劑型
- 錠劑
- 已知交互作用
- 53 (中度: 41 · 輕微: 12)
- 商品名
- 2
- 國家與市場
- 1
用途
作用方式
Thyroid hormones act by controlling DNA transcription and protein synthesis. T3 and T4 diffuse into the cell nucleus and bind to thyroid receptor proteins attached to DNA, activating gene transcription and messenger RNA synthesis.
成人常用劑量（仿單摘要）
Hypothyroidism: start 25 mcg orally once daily; increase by 25 mcg daily every 1 or 2 weeks if needed; usual maintenance 25 mcg to 75 mcg once daily
懷孕與哺乳
- 懷孕
- Safe Post-marketing data have not shown more birth defects or miscarriage. Untreated hypothyroidism harms mother and fetus, so do not stop treatment: check TSH and adjust the dose during pregnancy. Levothyroxine is the usual first choice in pregnancy.
- 哺乳
- Safe Liothyronine (T3) is a normal component of milk; replacement doses are not a reason to stop breastfeeding (LactMed). US label: weigh benefits (insufficient data on infant effects). Levothyroxine is recommended for hypothyroidism while breastfeeding.
已通報的副作用
- Arrhythmias
- Headache
- Nervousness
- Insomnia
- Tremors
- Weight loss
黑框警語
- Not for treatment of obesity or for weight loss. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening toxicity, particularly with sympathomimetic amines.
禁忌症
- Uncorrected adrenal insufficiency
哪些人需要特別留意
- Cardiac adverse reactions in the elderly and patients with cardiovascular disease; start at lower doses
- Not for myxedema coma; use intravenous thyroid hormone products
- Acute adrenal crisis in adrenal insufficiency; give glucocorticoids first
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (53)
- Alogliptin-metformin + Liothyronine Moderate
- Amitriptyline + Liothyronine Moderate
- Amobarbital + Liothyronine Moderate
- Canagliflozin-metformin + Liothyronine Moderate
- Carbamazepine + Liothyronine Moderate
- Carbonyl iron + Liothyronine Moderate
- Cholestyramine + Liothyronine Moderate
- Clomipramine + Liothyronine Moderate
- Colesevelam + Liothyronine Moderate
- Dapagliflozin-metformin + Liothyronine Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Liothyronine 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
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同類別的其他藥品
常見問題
What is Liothyronine used for?
Liothyronine is a medicine in the class endocrine. It is used for Hypothyroidism, Thyroid cancer.
What side effects have been reported with Liothyronine?
Arrhythmias, Headache, Nervousness, Insomnia, Tremors, Weight loss. Serious warning: Not for treatment of obesity or for weight loss.
Can Liothyronine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Post-marketing data have not shown more birth defects or miscarriage. Untreated hypothyroidism harms mother and fetus, so do not stop treatment: check TSH and adjust the dose during pregnancy. Levothyroxine is the usual first choice in pregnancy. Breastfeeding: Safe. Liothyronine (T3) is a normal component of milk; replacement doses are not a reason to stop breastfeeding (LactMed). US label: weigh benefits (insufficient data on infant effects). Levothyroxine is recommended for hypothyroidism while breastfeeding.
What does Liothyronine interact with?
MediHelp lists 53 known interactions for Liothyronine. Moderate: 41 · Minor: 12. The most serious include Alogliptin-metformin, Amitriptyline, Amobarbital.
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