藥品參考
Coagulation factor x
Coagulation factor x is a medicine in the class miscellaneous.
- 藥物類別: Miscellaneous
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- ATC 代碼
- B02BD13
- 商品名
- 1
- 國家與市場
- 1
作用方式
Temporarily replaces the missing Factor X needed for effective hemostasis. Factor X is activated to Factor Xa, which with Factor Va forms the prothrombinase complex that converts prothrombin to thrombin, leading to a cross-linked fibrin clot.
成人常用劑量(仿單摘要)
Routine prophylaxis of bleeding episodes (adults and adolescents 12 years or older): 25 IU/kg IV twice weekly; adjust to clinical response; do not administer more than 60 IU/kg daily
懷孕與哺乳
- 懷孕
- Unknown Limited human data and no animal studies. Factor X deficiency itself raises the risk of bleeding and miscarriage, so use when clearly needed under a specialist.
- 哺乳
- Unknown No data on milk levels or effects on the infant. A large plasma protein, unlikely to be absorbed by the infant. Weigh the benefits of breastfeeding against the mother's need for treatment.
已通報的副作用
- Infusion site erythema
- Infusion site pain
- Fatigue
- Back pain
禁忌症
- Life-threatening hypersensitivity reactions to COAGADEX
哪些人需要特別留意
- Hypersensitivity reactions including anaphylaxis are possible; discontinue and treat if symptoms occur
- Neutralizing antibodies (inhibitors) may develop; if expected Factor X levels are not attained or bleeding is uncontrolled, assay for inhibitor
- Made from human blood; may transmit infectious agents including viruses and vCJD/CJD agents
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用,即可開啟 Coagulation factor x 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
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同類別的其他藥品
常見問題
What is Coagulation factor x used for?
Coagulation factor x is a medicine in the class miscellaneous.
What side effects have been reported with Coagulation factor x?
Infusion site erythema, Infusion site pain, Fatigue, Back pain.
Can Coagulation factor x be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data and no animal studies. Factor X deficiency itself raises the risk of bleeding and miscarriage, so use when clearly needed under a specialist. Breastfeeding: Unknown. No data on milk levels or effects on the infant. A large plasma protein, unlikely to be absorbed by the infant. Weigh the benefits of breastfeeding against the mother's need for treatment.
What does Coagulation factor x interact with?
MediHelp does not list a checked interaction for Coagulation factor x yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。