藥品參考
Epoetin
Epoetin is a medicine in the class miscellaneous. It is used for anemia.
- 藥物類別: Miscellaneous
- 用途: anemia
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- 常見劑型
- 注射劑
- 商品名
- 3
- 國家與市場
- 1
用途
作用方式
Epoetin alfa products stimulate erythropoiesis by the same mechanism as endogenous erythropoietin.
成人常用劑量(仿單摘要)
Anemia due to CKD (adults on dialysis or not on dialysis): starting dose 50 to 100 Units/kg 3 times weekly, intravenously or subcutaneously; intravenous route recommended for hemodialysis patients; individualize dosing and use the lowest dose sufficient to reduce RBC transfusions
懷孕與哺乳
- 懷孕
- Unknown Limited human data; reports in women with kidney disease or anaemia have not reliably shown drug-related harm. In rats, doses near the starting dose caused embryo loss and skeletal and growth effects. Use only if needed; avoid benzyl alcohol (multi-dose) vials.
- 哺乳
- Safe Erythropoietin is a normal part of milk and the drug is poorly absorbed by the infant. LactMed: no special precautions with preservative-free vials. US label: multi-dose vials (benzyl alcohol) are contraindicated; avoid breastfeeding for 2 weeks after such a dose.
已通報的副作用
- Hypertension
- Arthralgia
- Pyrexia
- Nausea
- Vomiting
- Cough
黑框警語
- ESAs increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence. CKD: greater risks of death, serious cardiovascular reactions and stroke when targeting hemoglobin above 11 g/dL; no target or dosing strategy avoids these risks; use the lowest dose sufficient to reduce transfusions. Cancer: shortened overall survival and/or increased tumor progression or recurrence in breast, non-small cell lung, head and neck, lymphoid and cervical cancers; use only for anemia from myelosuppressive chemotherapy, not when…
禁忌症
- Uncontrolled hypertension
- Pure red cell aplasia that begins after treatment with RETACRIT or other erythropoietin protein drugs
- Serious allergic reactions to RETACRIT or other epoetin alfa products
哪些人需要特別留意
- Increased mortality, MI, stroke and thromboembolism when targeting hemoglobin above 11 g/dL; use caution in coexistent cardiovascular disease and stroke
- Hypertension: control prior to initiating and during treatment
- Seizures: increased risk in CKD; monitor for changes in seizure frequency
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用,即可開啟 Epoetin 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
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同類別的其他藥品
常見問題
What is Epoetin used for?
Epoetin is a medicine in the class miscellaneous. It is used for Anemia.
What side effects have been reported with Epoetin?
Hypertension, Arthralgia, Pyrexia, Nausea, Vomiting, Cough. Serious warning: ESAs increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence.
Can Epoetin be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data; reports in women with kidney disease or anaemia have not reliably shown drug-related harm. In rats, doses near the starting dose caused embryo loss and skeletal and growth effects. Use only if needed; avoid benzyl alcohol (multi-dose) vials. Breastfeeding: Safe. Erythropoietin is a normal part of milk and the drug is poorly absorbed by the infant. LactMed: no special precautions with preservative-free vials. US label: multi-dose vials (benzyl alcohol) are contraindicated; avoid breastfeeding for 2 weeks after such a dose.
What does Epoetin interact with?
MediHelp does not list a checked interaction for Epoetin yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。