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藥品參考

Epoetin

Epoetin is a medicine in the class miscellaneous. It is used for anemia.

最後更新 來源: US FDA label

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Miscellaneous
常見劑型
注射劑
商品名
3
國家與市場
1

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Epoetin alfa products stimulate erythropoiesis by the same mechanism as endogenous erythropoietin.

成人常用劑量(仿單摘要)

Anemia due to CKD (adults on dialysis or not on dialysis): starting dose 50 to 100 Units/kg 3 times weekly, intravenously or subcutaneously; intravenous route recommended for hemodialysis patients; individualize dosing and use the lowest dose sufficient to reduce RBC transfusions

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Limited human data; reports in women with kidney disease or anaemia have not reliably shown drug-related harm. In rats, doses near the starting dose caused embryo loss and skeletal and growth effects. Use only if needed; avoid benzyl alcohol (multi-dose) vials.
哺乳
Safe Erythropoietin is a normal part of milk and the drug is poorly absorbed by the infant. LactMed: no special precautions with preservative-free vials. US label: multi-dose vials (benzyl alcohol) are contraindicated; avoid breastfeeding for 2 weeks after such a dose.

已通報的副作用

  • Hypertension
  • Arthralgia
  • Pyrexia
  • Nausea
  • Vomiting
  • Cough

黑框警語

  • ESAs increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence. CKD: greater risks of death, serious cardiovascular reactions and stroke when targeting hemoglobin above 11 g/dL; no target or dosing strategy avoids these risks; use the lowest dose sufficient to reduce transfusions. Cancer: shortened overall survival and/or increased tumor progression or recurrence in breast, non-small cell lung, head and neck, lymphoid and cervical cancers; use only for anemia from myelosuppressive chemotherapy, not when…

禁忌症

  • Uncontrolled hypertension
  • Pure red cell aplasia that begins after treatment with RETACRIT or other erythropoietin protein drugs
  • Serious allergic reactions to RETACRIT or other epoetin alfa products

哪些人需要特別留意

  • Increased mortality, MI, stroke and thromboembolism when targeting hemoglobin above 11 g/dL; use caution in coexistent cardiovascular disease and stroke
  • Hypertension: control prior to initiating and during treatment
  • Seizures: increased risk in CKD; monitor for changes in seizure frequency

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Epoetin 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Dosing in older adults
  • How to give it
  • Pharmacokinetics
  • Patient counselling points
  • IV preparation and dilution

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同類別的其他藥品

常見問題

What is Epoetin used for?

Epoetin is a medicine in the class miscellaneous. It is used for Anemia.

What side effects have been reported with Epoetin?

Hypertension, Arthralgia, Pyrexia, Nausea, Vomiting, Cough. Serious warning: ESAs increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence.

Can Epoetin be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Limited human data; reports in women with kidney disease or anaemia have not reliably shown drug-related harm. In rats, doses near the starting dose caused embryo loss and skeletal and growth effects. Use only if needed; avoid benzyl alcohol (multi-dose) vials. Breastfeeding: Safe. Erythropoietin is a normal part of milk and the drug is poorly absorbed by the infant. LactMed: no special precautions with preservative-free vials. US label: multi-dose vials (benzyl alcohol) are contraindicated; avoid breastfeeding for 2 weeks after such a dose.

What does Epoetin interact with?

MediHelp does not list a checked interaction for Epoetin yet. Always tell your pharmacist about every medicine you take.

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