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藥品參考

Eflapegrastim

Eflapegrastim is a medicine in the class miscellaneous. It is used for febrile neutropenia.

最後更新 來源: US FDA label

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Miscellaneous
常見劑型
注射劑
常見規格
13.2 mg/.6 ml
商品名
1
國家與市場
1

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Recombinant human granulocyte growth factor that binds G-CSF receptors on myeloid progenitor cells and neutrophils, triggering signaling that controls differentiation, proliferation, migration and survival.

成人常用劑量(仿單摘要)

Decrease incidence of febrile neutropenia in non-myeloid malignancies on myelosuppressive chemotherapy: 13.2 mg, subcutaneous, once per chemotherapy cycle, approximately 24 hours after cytotoxic chemotherapy; do not give from 14 days before to 24 hours after chemotherapy

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown No human data on Rolvedon; other rhG-CSF products showed no identified drug-associated risk in published studies. In rabbits, embryofetal lethality and reduced fetal weight occurred at approximately 6 times clinical exposure.
哺乳
Unknown No data on presence in human milk; other rhG-CSF products are present at low levels. Consider breastfeeding benefits along with maternal clinical need.

已通報的副作用

  • Fatigue
  • Nausea
  • Diarrhea
  • Bone pain
  • Headache
  • Pyrexia

禁忌症

  • History of serious allergic reactions to eflapegrastim, pegfilgrastim, or filgrastim products (may include anaphylaxis).

哪些人需要特別留意

  • Splenic rupture, including fatal cases; evaluate for enlarged spleen if left upper abdominal or shoulder pain.
  • ARDS: evaluate patients with fever, lung infiltrates or respiratory distress; discontinue if ARDS.
  • Serious allergic reactions including anaphylaxis: permanently discontinue.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Eflapegrastim 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • How to give it
  • Pharmacokinetics
  • Patient counselling points

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同類別的其他藥品

常見問題

What is Eflapegrastim used for?

Eflapegrastim is a medicine in the class miscellaneous. It is used for Febrile neutropenia.

What side effects have been reported with Eflapegrastim?

Fatigue, Nausea, Diarrhea, Bone pain, Headache, Pyrexia.

Can Eflapegrastim be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. No human data on Rolvedon; other rhG-CSF products showed no identified drug-associated risk in published studies. In rabbits, embryofetal lethality and reduced fetal weight occurred at approximately 6 times clinical exposure. Breastfeeding: Unknown. No data on presence in human milk; other rhG-CSF products are present at low levels. Consider breastfeeding benefits along with maternal clinical need.

What does Eflapegrastim interact with?

MediHelp does not list a checked interaction for Eflapegrastim yet. Always tell your pharmacist about every medicine you take.

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