藥品參考
Desloratadine
Desloratadine is a medicine in the class respiratory. It is used for allergic rhinitis.
- 藥物類別: Respiratory
- 用途: allergic rhinitis
最後更新 來源: US FDA label, EMA SmPC, Health Canada product monograph
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Respiratory
- ATC 代碼
- R06AX27
- 常見劑型
- 錠劑, 糖漿, 溶液
- 常見規格
- 5 mg, 2.5 mg/5 ml, 0.5 mg/ml
- 已知交互作用
- 38 (中度: 4 · 輕微: 34)
- 商品名
- 107
- 國家與市場
- 6
用途
作用方式
Like other H1-blockers, Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms (eg. nasal congestion, watery eyes) brought on by histamine.
成人常用劑量（仿單摘要）
5 mg once in the evening.
懷孕與哺乳
- 懷孕
- Unknown Limited human data; no harm in rats at relevant doses. Data for loratadine, of which it is the active metabolite, are reassuring. Loratadine or cetirizine, which have more pregnancy data, are preferred.
- 哺乳
- Safe Passes into milk. US label: decide whether to stop breastfeeding or the drug. LactMed: low milk levels expected and it is non-sedating, so infant harm is unlikely; it may reduce milk supply if combined with pseudoephedrine.
已通報的副作用
- Headache
- Diarrhea
- Fever
- Irritability
禁忌症
- Documented hypersensitivity to desloratadine or loratadine or components
哪些人需要特別留意
- May potentiate effect of sedatives, including alcohol
- Caution in slow metabolizers; may increase incidence of side effects
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (38)
- Desloratadine + Erdafitinib Moderate
- Desloratadine + Isocarboxazid Moderate
- Desloratadine + Tranylcypromine Moderate
- Desloratadine + Zuranolone Moderate
- Amifampridine + Desloratadine Minor
- Berotralstat + Desloratadine Minor
- Bosutinib + Desloratadine Minor
- Cenobamate + Desloratadine Minor
- Crizotinib + Desloratadine Minor
- Danicopan + Desloratadine Minor
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Desloratadine 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同類別的其他藥品
常見問題
What is Desloratadine used for?
Desloratadine is a medicine in the class respiratory. It is used for Allergic rhinitis, Common cold, Urticaria.
What side effects have been reported with Desloratadine?
Headache, Diarrhea, Fever, Irritability.
Can Desloratadine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data; no harm in rats at relevant doses. Data for loratadine, of which it is the active metabolite, are reassuring. Loratadine or cetirizine, which have more pregnancy data, are preferred. Breastfeeding: Safe. Passes into milk. US label: decide whether to stop breastfeeding or the drug. LactMed: low milk levels expected and it is non-sedating, so infant harm is unlikely; it may reduce milk supply if combined with pseudoephedrine.
What does Desloratadine interact with?
MediHelp lists 38 known interactions for Desloratadine. Moderate: 4 · Minor: 34. The most serious include Erdafitinib, Isocarboxazid, Tranylcypromine.
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