藥物交互作用
Desloratadine + Tranylcypromine
嚴重程度: 中度
Desloratadine and Tranylcypromine: moderate interaction.
最後更新
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摘要
MAO inhibitors may intensify and prolong the anticholinergic and sedative effects of antihistamines. Desloratadine is non-sedating at usual doses, so the effect is generally mild.
用白話說明這項交互作用的意義
Desloratadine and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desloratadine belongs to Respiratory; Tranylcypromine belongs to Central Nervous System.
為什麼會發生
Additive pharmacodynamic CNS depression, with MAO inhibition possibly potentiating antihistamine anticholinergic effects.
處置方式
Monitor for drowsiness and anticholinergic symptoms such as dry mouth or urinary retention. Advise caution with driving until the response is known.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Desloratadine 的其他交互作用
Tranylcypromine 的其他交互作用
常見問題
Can I take Desloratadine with Tranylcypromine?
MediHelp rates the interaction as moderate. Desloratadine and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. MAO inhibitors may intensify and prolong the anticholinergic and sedative effects of antihistamines. Desloratadine is non-sedating at usual doses, so the effect is generally mild.
How serious is the interaction between Desloratadine and Tranylcypromine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for drowsiness and anticholinergic symptoms such as dry mouth or urinary retention. Advise caution with driving until the response is known.
What other medicines interact with Desloratadine?
MediHelp also lists interactions of Desloratadine with, for example, Erdafitinib, Isocarboxazid, Zuranolone. The full list is on the Desloratadine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
