藥物交互作用
Desloratadine + Zuranolone
嚴重程度: 中度
Desloratadine and Zuranolone: moderate interaction.
最後更新
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摘要
Zuranolone causes significant somnolence and impaired driving ability. Desloratadine is minimally sedating, so any additional effect is likely small, but additive CNS effects are possible.
用白話說明這項交互作用的意義
Desloratadine and Zuranolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desloratadine belongs to Respiratory; Zuranolone belongs to Central Nervous System.
為什麼會發生
Additive CNS depression, predominantly from zuranolone's GABA-A modulation.
處置方式
Counsel on sedation and driving impairment. Reduce the zuranolone dose if excessive sedation occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Desloratadine 的其他交互作用
Zuranolone 的其他交互作用
常見問題
Can I take Desloratadine with Zuranolone?
MediHelp rates the interaction as moderate. Desloratadine and Zuranolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zuranolone causes significant somnolence and impaired driving ability. Desloratadine is minimally sedating, so any additional effect is likely small, but additive CNS effects are possible.
How serious is the interaction between Desloratadine and Zuranolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on sedation and driving impairment. Reduce the zuranolone dose if excessive sedation occurs.
What other medicines interact with Desloratadine?
MediHelp also lists interactions of Desloratadine with, for example, Erdafitinib, Isocarboxazid, Tranylcypromine. The full list is on the Desloratadine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
