藥品參考
Ephedrine
Ephedrine is a medicine in the class cardiovascular. It is used for hypotension.
- 藥物類別: Cardiovascular
- 用途: hypotension
最後更新 來源: US FDA label
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 錠劑, 注射劑
- 常見規格
- 5 mg/ml, 12.5 mg, 25 mg
- 已知交互作用
- 170 (禁忌併用: 6 · 嚴重: 6 · 中度: 88 · 輕微: 70)
- 商品名
- 5
- 國家與市場
- 2
用途
作用方式
Sympathomimetic amine that directly agonizes alpha- and beta-adrenergic receptors and indirectly causes norepinephrine release from sympathetic neurons, raising arterial pressure, cardiac output and peripheral resistance.
成人常用劑量（仿單摘要）
Clinically important hypotension in the setting of anesthesia: initial 5 mg to 10 mg IV bolus; additional boluses as needed; titrate to blood pressure goal; total not to exceed 50 mg
懷孕與哺乳
- 懷孕
- Unknown Available human data have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; neonatal metabolic acidosis reported with maternal exposure, so monitor newborn. Animal decreased fetal survival and weight occurred with maternal toxicity.
- 哺乳
- Unknown Ephedrine is present in human milk in a single case report; effects on infant and milk production unknown. Weigh breastfeeding benefits against maternal need.
已通報的副作用
- Nausea
- Vomiting
- Tachycardia
- Palpitations
- Reactive hypertension
- Bradycardia
禁忌症
- None
哪些人需要特別留意
- Serious postpartum hypertension, some with stroke, reported with vasopressor plus oxytocic; monitor blood pressure carefully.
- Repeated administration can cause tachyphylaxis; have an alternative pressor ready.
- Prophylactic use to prevent hypotension is associated with increased incidence of hypertension compared with treatment of hypotension.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (170)
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
- Caffeine + Ephedrine Major
- Ephedrine + Ergotamine Major
- Ephedrine + Linezolid Major
- Ephedrine + Maprotiline Major
常見問題
What is Ephedrine used for?
Ephedrine is a medicine in the class cardiovascular. It is used for Hypotension.
What side effects have been reported with Ephedrine?
Nausea, Vomiting, Tachycardia, Palpitations, Reactive hypertension, Bradycardia.
Can Ephedrine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Available human data have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; neonatal metabolic acidosis reported with maternal exposure, so monitor newborn. Animal decreased fetal survival and weight occurred with maternal toxicity. Breastfeeding: Unknown. Ephedrine is present in human milk in a single case report; effects on infant and milk production unknown. Weigh breastfeeding benefits against maternal need.
What does Ephedrine interact with?
MediHelp lists 170 known interactions for Ephedrine. Contraindicated: 6 · Major: 6 · Moderate: 88 · Minor: 70. The most serious include Isocarboxazid, Phenelzine, Procarbazine.
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