藥物交互作用
Ephedrine + Linezolid
嚴重程度: 嚴重
Ephedrine and Linezolid: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ephedrine releases norepinephrine and linezolid reduces its breakdown, so pressor responses can be exaggerated. Severe hypertension may occur.
用白話說明這項交互作用的意義
Ephedrine and Linezolid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ephedrine belongs to Cardiovascular; Linezolid belongs to Anti Bacterial.
為什麼會發生
MAO inhibition enhances the indirect sympathomimetic effect of ephedrine.
處置方式
Avoid if possible; if a vasopressor is needed, use a low dose of a direct agent with careful blood pressure titration. Monitor blood pressure continuously.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Linezolid 的其他交互作用
Ephedrine 的其他交互作用
常見問題
Can I take Ephedrine with Linezolid?
MediHelp rates the interaction as major. Ephedrine and Linezolid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ephedrine releases norepinephrine and linezolid reduces its breakdown, so pressor responses can be exaggerated. Severe hypertension may occur.
How serious is the interaction between Ephedrine and Linezolid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; if a vasopressor is needed, use a low dose of a direct agent with careful blood pressure titration. Monitor blood pressure continuously.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。