藥物交互作用
Ephedrine + Procarbazine
嚴重程度: 禁忌併用
Ephedrine and Procarbazine: contraindicated interaction.
最後更新
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摘要
Ephedrine releases noradrenaline indirectly, and procarbazine inhibits MAO, so the pressor response may be markedly exaggerated. This may cause a hypertensive crisis, severe headache, and arrhythmias.
用白話說明這項交互作用的意義
Ephedrine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ephedrine belongs to Cardiovascular; Procarbazine belongs to Oncology.
為什麼會發生
MAO inhibition increases neuronal noradrenaline stores and prolongs the effect of indirect sympathomimetics.
處置方式
Avoid ephedrine and other sympathomimetics during and for 14 days after procarbazine. Use non-pressor alternatives for symptom relief.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Procarbazine 的其他交互作用
Ephedrine 的其他交互作用
常見問題
Can I take Ephedrine with Procarbazine?
MediHelp rates the interaction as contraindicated. Ephedrine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ephedrine releases noradrenaline indirectly, and procarbazine inhibits MAO, so the pressor response may be markedly exaggerated. This may cause a hypertensive crisis, severe headache, and arrhythmias.
How serious is the interaction between Ephedrine and Procarbazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ephedrine and other sympathomimetics during and for 14 days after procarbazine. Use non-pressor alternatives for symptom relief.
What other medicines interact with Procarbazine?
MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Amoxapine. The full list is on the Procarbazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
