藥品參考
Lunsotogene parvec
Lunsotogene parvec is a medicine in the class miscellaneous.
- 藥物類別: Miscellaneous
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- 常見劑型
- 注射劑
- 商品名
- 1
- 國家與市場
- 1
作用方式
Intracochlear infusion results in expression of the OTOF gene primarily in inner hair cells, which facilitates production of functional otoferlin protein and restores synaptic transmission to the auditory nerve (shown in mouse studies).
成人常用劑量（仿單摘要）
OTOF-associated severe-to-profound sensorineural hearing loss: 7.2 × 10 12 vector genomes (vg) per ear in a total volume of 0.24 mL, single-dose intracochlear infusion; bilateral treatment given in a single surgical session
懷孕與哺乳
- 懷孕
- Unknown Gene therapy given once by infusion into the inner ear for OTOF-related deafness. No data in pregnancy and no animal reproduction studies. Confirm a negative pregnancy test before treatment in women who could become pregnant.
- 哺乳
- Unknown No data on passage into milk, effects on the breastfed infant or milk production. Most patients are children; for an adult mother, discuss with the treating team before breastfeeding.
已通報的副作用
- Otitis media
- Vomiting
- Nausea
- Dizziness
- Procedural pain
- Gait disturbance
哪些人需要特別留意
- Procedure-related adverse reactions may occur, including vertigo, tinnitus, CSF leak, facial paresis, taste change, meningitis, wound infection, mastoiditis, numbness around the ear, and labyrinthitis; monitor and manage
- Not recommended when preoperative imaging shows inner ear access is not feasible (e.g., abnormal mastoid pneumatization or anatomic variations)
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Lunsotogene parvec 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Lunsotogene parvec used for?
Lunsotogene parvec is a medicine in the class miscellaneous.
What side effects have been reported with Lunsotogene parvec?
Otitis media, Vomiting, Nausea, Dizziness, Procedural pain, Gait disturbance.
Can Lunsotogene parvec be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Gene therapy given once by infusion into the inner ear for OTOF-related deafness. No data in pregnancy and no animal reproduction studies. Confirm a negative pregnancy test before treatment in women who could become pregnant. Breastfeeding: Unknown. No data on passage into milk, effects on the breastfed infant or milk production. Most patients are children; for an adult mother, discuss with the treating team before breastfeeding.
What does Lunsotogene parvec interact with?
MediHelp does not list a checked interaction for Lunsotogene parvec yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
