藥物交互作用
Canagliflozin-metformin + Mecasermin
嚴重程度: 中度
Canagliflozin-metformin and Mecasermin: moderate interaction.
最後更新
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摘要
Mecasermin is recombinant IGF-1 and has insulin-like hypoglycemic effects. Combined with canagliflozin-metformin, glucose lowering may be additive and hypoglycemia may occur.
用白話說明這項交互作用的意義
Canagliflozin-metformin and Mecasermin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Canagliflozin-metformin belongs to Endocrine; Mecasermin belongs to Endocrine.
為什麼會發生
IGF-1 receptor activation promotes glucose uptake, adding to the effect of antidiabetic drugs.
處置方式
Give mecasermin with or shortly after a meal and monitor blood glucose. Adjust antidiabetic doses if hypoglycemia occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Canagliflozin-metformin 的其他交互作用
Mecasermin 的其他交互作用
常見問題
Can I take Canagliflozin-metformin with Mecasermin?
MediHelp rates the interaction as moderate. Canagliflozin-metformin and Mecasermin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mecasermin is recombinant IGF-1 and has insulin-like hypoglycemic effects. Combined with canagliflozin-metformin, glucose lowering may be additive and hypoglycemia may occur.
How serious is the interaction between Canagliflozin-metformin and Mecasermin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give mecasermin with or shortly after a meal and monitor blood glucose. Adjust antidiabetic doses if hypoglycemia occurs.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
