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藥品參考

Milrinone

Milrinone is a medicine in the class cardiovascular. It is used for congestive heart failure.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Cardiovascular
常見劑型
注射劑
常見規格
0.2 mg/ml, 1 mg/ml, 10 mg/10 ml
已知交互作用
8 (嚴重: 6 · 輕微: 2)
商品名
5
國家與市場
4

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Phosphodiesterase inhibitor; positive inotrope with little chronotropic effect; direct vasodilator (decreases both preload and afterload)

成人常用劑量(仿單摘要)

Congestive Heart Failure: 50 mcg/kg loading dose by IV push over 10 minutes, then 0.375-0.75 mcg/kg/min IV, Maintenance: 1.13 mg/kg/day

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Limited human data; no birth defects in rats or rabbits. Used short-term IV for severe heart failure when the mother's condition requires it.
哺乳
Unknown Not known if it passes into milk; no LactMed record. US label: use with caution. e-lactancia: likely to pass into milk and newborns clear it slowly; prefer an alternative, or pump and discard and wait 8 to 10 hours after a dose before nursing.

已通報的副作用

  • Headache
  • Hypotension
  • Ventricular arrhythmias
  • Supraventricular arrhythmia
  • Angina/chest pain

禁忌症

  • Hypersensitivity to milrinone and inamrinone

哪些人需要特別留意

  • Discontinue therapy if symptoms of hepatotoxicity (eg., increased LFTs) occur; monitor liver function
  • Ensure that ventricular rate is controlled in atrial fibrillation/flutter before initiating therapy; may increase ventricular response rate
  • Severe aortic or pulmonic obstruction, acute phase after myocardial infarction (MI)

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

重要交互作用 (8)

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Milrinone 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions
  • IV preparation and dilution

在網頁版免費試用 Pro+ 14 天,無需信用卡。

同類別的其他藥品

常見問題

What is Milrinone used for?

Milrinone is a medicine in the class cardiovascular. It is used for Congestive heart failure.

What side effects have been reported with Milrinone?

Headache, Hypotension, Ventricular arrhythmias, Supraventricular arrhythmia, Angina/chest pain.

Can Milrinone be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Limited human data; no birth defects in rats or rabbits. Used short-term IV for severe heart failure when the mother's condition requires it. Breastfeeding: Unknown. Not known if it passes into milk; no LactMed record. US label: use with caution. e-lactancia: likely to pass into milk and newborns clear it slowly; prefer an alternative, or pump and discard and wait 8 to 10 hours after a dose before nursing.

What does Milrinone interact with?

MediHelp lists 8 known interactions for Milrinone. Major: 6 · Minor: 2. The most serious include Anagrelide, Cilostazol, Enoximone.

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