藥品參考
Milrinone
Milrinone is a medicine in the class cardiovascular. It is used for congestive heart failure.
- 藥物類別: Cardiovascular
- 用途: congestive heart failure
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 注射劑
- 常見規格
- 0.2 mg/ml, 1 mg/ml, 10 mg/10 ml
- 已知交互作用
- 8 (嚴重: 6 · 輕微: 2)
- 商品名
- 5
- 國家與市場
- 4
用途
作用方式
Phosphodiesterase inhibitor; positive inotrope with little chronotropic effect; direct vasodilator (decreases both preload and afterload)
成人常用劑量(仿單摘要)
Congestive Heart Failure: 50 mcg/kg loading dose by IV push over 10 minutes, then 0.375-0.75 mcg/kg/min IV, Maintenance: 1.13 mg/kg/day
懷孕與哺乳
- 懷孕
- Unknown Limited human data; no birth defects in rats or rabbits. Used short-term IV for severe heart failure when the mother's condition requires it.
- 哺乳
- Unknown Not known if it passes into milk; no LactMed record. US label: use with caution. e-lactancia: likely to pass into milk and newborns clear it slowly; prefer an alternative, or pump and discard and wait 8 to 10 hours after a dose before nursing.
已通報的副作用
- Headache
- Hypotension
- Ventricular arrhythmias
- Supraventricular arrhythmia
- Angina/chest pain
禁忌症
- Hypersensitivity to milrinone and inamrinone
哪些人需要特別留意
- Discontinue therapy if symptoms of hepatotoxicity (eg., increased LFTs) occur; monitor liver function
- Ensure that ventricular rate is controlled in atrial fibrillation/flutter before initiating therapy; may increase ventricular response rate
- Severe aortic or pulmonic obstruction, acute phase after myocardial infarction (MI)
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。
重要交互作用 (8)
- Anagrelide + Milrinone Major
- Cilostazol + Milrinone Major
- Enoximone + Milrinone Major
- Inamrinone + Milrinone Major
- Milrinone + Olprinone Major
- Milrinone + Riociguat Major
- Milrinone + Ozanimod Minor
- Milrinone + Ponesimod Minor
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用,即可開啟 Milrinone 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天,無需信用卡。
同類別的其他藥品
常見問題
What is Milrinone used for?
Milrinone is a medicine in the class cardiovascular. It is used for Congestive heart failure.
What side effects have been reported with Milrinone?
Headache, Hypotension, Ventricular arrhythmias, Supraventricular arrhythmia, Angina/chest pain.
Can Milrinone be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data; no birth defects in rats or rabbits. Used short-term IV for severe heart failure when the mother's condition requires it. Breastfeeding: Unknown. Not known if it passes into milk; no LactMed record. US label: use with caution. e-lactancia: likely to pass into milk and newborns clear it slowly; prefer an alternative, or pump and discard and wait 8 to 10 hours after a dose before nursing.
What does Milrinone interact with?
MediHelp lists 8 known interactions for Milrinone. Major: 6 · Minor: 2. The most serious include Anagrelide, Cilostazol, Enoximone.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。