藥物交互作用
Milrinone + Ponesimod
嚴重程度: 輕微
Milrinone and Ponesimod: minor interaction.
最後更新
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摘要
Ponesimod slows heart rate on initiation, while milrinone is an inotrope with vasodilating and arrhythmogenic properties. No established additive bradycardia exists, but the combination occurs in patients with significant cardiac disease in whom hemodynamic instability is a concern.
用白話說明這項交互作用的意義
Milrinone and Ponesimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Milrinone belongs to Cardiovascular; Ponesimod belongs to Central Nervous System.
為什麼會發生
No established interaction; the drugs have differing hemodynamic effects via S1P receptor modulation and PDE3 inhibition.
處置方式
Monitor heart rate, blood pressure and ECG when ponesimod is started in a patient receiving milrinone, and involve cardiology if there is significant cardiac disease.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Milrinone 的其他交互作用
Ponesimod 的其他交互作用
常見問題
Can I take Milrinone with Ponesimod?
MediHelp rates the interaction as minor. Milrinone and Ponesimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ponesimod slows heart rate on initiation, while milrinone is an inotrope with vasodilating and arrhythmogenic properties. No established additive bradycardia exists, but the combination occurs in patients with significant cardiac disease in whom hemodynamic instability is a concern.
How serious is the interaction between Milrinone and Ponesimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG when ponesimod is started in a patient receiving milrinone, and involve cardiology if there is significant cardiac disease.
What other medicines interact with Milrinone?
MediHelp also lists interactions of Milrinone with, for example, Anagrelide, Cilostazol, Enoximone. The full list is on the Milrinone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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