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藥品參考

Miltefosine

Miltefosine is a medicine in the class anti parasitic. It is used for leishmaniasis.

最後更新 來源: US FDA label

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Anti Parasitic
常見劑型
膠囊
常見規格
50 mg
商品名
2
國家與市場
1

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Miltefosine is an anti-leishmanial agent.

成人常用劑量(仿單摘要)

Visceral, cutaneous and mucosal leishmaniasis, weight 30 kg to 44 kg: one 50 mg capsule orally twice daily with food (breakfast and dinner) for 28 consecutive days

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unsafe Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing.
哺乳
Unsafe Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.

已通報的副作用

  • Vomiting
  • Nausea
  • Diarrhea
  • Decreased appetite
  • Headache
  • Dizziness

黑框警語

  • Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose. Do not give to pregnant women. Obtain a serum or urine pregnancy test in females of reproductive potential before prescribing. Advise effective contraception during therapy and for 5 months after therapy.

禁忌症

  • Pregnancy
  • Sjögren-Larsson-Syndrome
  • Hypersensitivity to miltefosine or any of its excipients

哪些人需要特別留意

  • Reproductive effects: testicular atrophy and impaired fertility in male rats and impaired fertility in female rats; effects on human fertility not adequately evaluated.
  • Renal effects: serum creatinine elevations; monitor renal function weekly during therapy and for 4 weeks after.
  • Hepatic effects: monitor ALT, AST and bilirubin during therapy.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

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解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Miltefosine 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • How to give it
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions

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同類別的其他藥品

常見問題

What is Miltefosine used for?

Miltefosine is a medicine in the class anti parasitic. It is used for Leishmaniasis.

What side effects have been reported with Miltefosine?

Vomiting, Nausea, Diarrhea, Decreased appetite, Headache, Dizziness. Serious warning: Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose.

Can Miltefosine be taken in pregnancy or while breastfeeding?

Pregnancy: Unsafe. Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing. Breastfeeding: Unsafe. Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.

What does Miltefosine interact with?

MediHelp does not list a checked interaction for Miltefosine yet. Always tell your pharmacist about every medicine you take.

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