藥品參考
Miltefosine
Miltefosine is a medicine in the class anti parasitic. It is used for leishmaniasis.
- 藥物類別: Anti Parasitic
- 用途: leishmaniasis
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Parasitic
- 常見劑型
- 膠囊
- 常見規格
- 50 mg
- 商品名
- 2
- 國家與市場
- 1
用途
作用方式
Miltefosine is an anti-leishmanial agent.
成人常用劑量(仿單摘要)
Visceral, cutaneous and mucosal leishmaniasis, weight 30 kg to 44 kg: one 50 mg capsule orally twice daily with food (breakfast and dinner) for 28 consecutive days
懷孕與哺乳
- 懷孕
- Unsafe Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing.
- 哺乳
- Unsafe Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
已通報的副作用
- Vomiting
- Nausea
- Diarrhea
- Decreased appetite
- Headache
- Dizziness
黑框警語
- Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose. Do not give to pregnant women. Obtain a serum or urine pregnancy test in females of reproductive potential before prescribing. Advise effective contraception during therapy and for 5 months after therapy.
禁忌症
- Pregnancy
- Sjögren-Larsson-Syndrome
- Hypersensitivity to miltefosine or any of its excipients
哪些人需要特別留意
- Reproductive effects: testicular atrophy and impaired fertility in male rats and impaired fertility in female rats; effects on human fertility not adequately evaluated.
- Renal effects: serum creatinine elevations; monitor renal function weekly during therapy and for 4 weeks after.
- Hepatic effects: monitor ALT, AST and bilirubin during therapy.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用,即可開啟 Miltefosine 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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常見問題
What is Miltefosine used for?
Miltefosine is a medicine in the class anti parasitic. It is used for Leishmaniasis.
What side effects have been reported with Miltefosine?
Vomiting, Nausea, Diarrhea, Decreased appetite, Headache, Dizziness. Serious warning: Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose.
Can Miltefosine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing. Breastfeeding: Unsafe. Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
What does Miltefosine interact with?
MediHelp does not list a checked interaction for Miltefosine yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。